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Bio II Ch. 15 Vocabulary

Matching
 
 
15.1 Vocabulary
a.
Archibald Garrod
e.
Vernon Ingram
b.
inborn error of metabolism
f.
one gene - one polypeptide hypothesis
c.
George Beadle and Edward Tatum
g.
Linus Pauling and Harvey Itano
d.
one gene - one enzyme hypothesis
 

 1. 

a phrase dramatizing the relationship when family members often have the same disorder
 

 2. 

there is a gene for each type of peptide chain
 

 3. 

worked with red bread mold to determine pathways exist in the biosynthesis of molecules
 

 4. 

ran an electrophoresis gel to determine if there was a charge diffference between normal red blood cells and sickled red blood cells
 

 5. 

determined the structural difference between normal red blood cells and sickled red blood cells
 

 6. 

suggested there is a relationship between inheritance and metabolic diseases
 

 7. 

each gene specifies the synthesis of one enzyme
 
 
15.2 Vocabulary
a.
messenger RNA
e.
translation
b.
ribosomal RNA
f.
DNA
c.
transfer RNA
g.
RNA
d.
transcription
h.
Central Dogma
 

 8. 

transfers amino acids to the ribosomes
 

 9. 

process which an mRNA transcript directs the sequence of amino acids in a polypeptide
 

 10. 

a molecule that is double stranded
 

 11. 

takes the message from DNA in the nucleus to the ribosomes in the cytoplasm
 

 12. 

explains the manner in which genes are expressed; DNA to RNA to protein
 

 13. 

a molecule that is single stranded
 

 14. 

along with proteins, makes up the ribosomes, where proteins are synthesized
 

 15. 

process by which an RNA copy is made of a portion of DNA
 
 
15.3 Vocabulary
a.
codon
d.
qualities of genetic material
b.
Marshall Nirenberg; J. Heinrich Matthei
e.
triplet code
c.
Marshall Nirenberg; Philip Leder
 

 16. 

laid the groundwork for cracking the genetic code
 

 17. 

a code word sequence of three nitrogen bases on messenger RNA
 

 18. 

developed a cell free system to determine the sequence of three nucleotides at a time
 

 19. 

each codon consists of three nucleotide bases, not 1, 2, or 4
 

 20. 

must be degenerate, unambiguous, and have start and stop signals
 
 
15.4 Vocabulary
a.
promoter
e.
ribozymes
b.
RNA polymerase
f.
spliceosomes
c.
exons
g.
mRNA cap
d.
introns
h.
mRNA poly-A tail
 

 21. 

RNA with an enzymatic function, can “self-splice”
 

 22. 

a modified guanine put at the start of a processed mRNA molecule
 

 23. 

matches RNA nucleotides to a DNA template
 

 24. 

segments of the primary mRNA transcripts that are removed
 

 25. 

defines the start of a gene
 

 26. 

segments of the primary mRNA transcripts that are expressed
 

 27. 

a segment of repeating adenines at the end of a processed mRNA molecule
 

 28. 

cuts the primary mRNA and the rejoins the adjacent exons
 
 
15.5 Vocabulary
a.
anticodon
f.
three steps of translation
b.
wobble effect
g.
A site
c.
polyribosome
h.
P site
d.
tRNA synthetases
i.
translocation
e.
start codon
j.
E site
 

 29. 

matches the correct amino acid to the correct tRNA molecule
 

 30. 

a U in the third anticodon position can pair with an A or G in the third codon position
 

 31. 

the spot for the next tRNA molecule at the ribosome
 

 32. 

a group of three bases that is complementary to a specific codon of mRNA
 

 33. 

when a transfer RNA moves from the A site to the P site, and then to the E site
 

 34. 

chain initiation, chain elongation, and chain termination
 

 35. 

holds the tRNA so amino acids can link
 

 36. 

a complex of several ribosomes translating the same mRNA
 

 37. 

AUG; known as methionine
 

 38. 

exit site for the tRNA molocule at the ribosome
 
 
15.6 Vocabulary
a.
gene mutation
e.
point mutation
b.
reading frame
f.
silent mutation
c.
frameshift mutation
g.
missense mutation
d.
mutagens
h.
nonsense mutation
 

 39. 

adding or deleting a nitrogen base causing a shift in the reading frame; results in a completely new sequence of codons and a nonfunctional protein
 

 40. 

environmental substances that cause random DNA base changes
 

 41. 

a point mutation that still codes for the same amino acid
 

 42. 

a point mutation that still codes for the same amino acid
 

 43. 

the sequence of the codons when they are read from the starting point
 

 44. 

a point mutation which codes for a stop codon in the middle of a polypeptide
 

 45. 

a single change in a nucleotide and therefore a change in a specific codon
 

 46. 

a change in the nucleotide sequence of DNA
 



 
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